Evaluation of indirect sequence-specific magneto-extraction-aided LAMP for fluorescence and electrochemical SARS-CoV-2 nucleic acid detectionArticle Published on 2023-01-152022-11-15 Journal: Talanta [Category] SARS, 변종, 치료기술, 치료제, [키워드] amplification approach circumvent clinically Disadvantages Electrochemical LAMP Host in silico inhibitor investigated isothermal isothermal amplification Magnetic sequence-specific target enrichment molecular NAAT nucleic acid Nucleic acid detection PCR polymerase probe qRT-PCR Quantitative Quantitative real-time LAMP real-time reverse transcriptase restrict SARS-CoV-2 SARS-CoV-2 nucleic acid SARS-CoV-2 variant SARS-CoV-2. sensitivity sequence serum turn [DOI] 10.1016/j.talanta.2022.123809 PMC 바로가기
Reduction of ACE2 Serum Concentrations by Telbivudine in Chronic Hepatitis B PatientsArticle Published on 2023-01-012023-06-13 Journal: Current molecular medicine [Category] B형 간염, [키워드] ACE2 Angiotensin-converting enzyme Coronavirus disease 2019 Hepatitis B virus SARS-CoV-2 serum severe acute respiratory syndrome coronavirus 2 telbivudine. [DOI] 10.2174/1566524022666220510220533 PMC 바로가기
Detection of anti-NMDA receptor antibodies following BBIBP-CorV COVID-19 vaccination in a rituximab-treated person with multiple sclerosis presenting with manifestations of an acute relapse급성 재발의 징후를 나타내는 다발성 경화증을 가진 리툭시맙으로 치료받은 사람에서 BBIBP-CorV COVID-19 백신 접종 후 항-NMDA 수용체 항체 검출Article Published on 2022-12-312022-09-12 Journal: Human vaccines & immunotherapeutics [Category] MERS, 진단, [키워드] added administration Anti-N-methyl-D-aspartate receptor Anti-N-Methyl-d-Aspartate receptor antibodies anti-NMDAR antibodies antibody ataxic Autoimmune Autoimmune encephalitis Babinski sign BBIBP-CorV benefit Case report clinician corticosteroid pulse COVID-19 COVID-19 vaccination CSF analysis detection early diagnosis Encephalitis initiated manifestation MRI multiple sclerosis multiple sclerosis. Neurological symptom NMDAR Patient performed Physical examination plaques positive presenting receiving receptor second dose serum Sinopharm Symptoms tested therapy Vaccines worsening [DOI] 10.1080/21645515.2022.2033540 PMC 바로가기 [Article Type] Article
Serological indices and ultrasound variables in predicting the staging of hepatitis B liver fibrosis: A comparative study based on random forest algorithm and traditional methodsArticle Published on 2022-12-012023-06-09 Journal: Journal of cancer research and therapeutics [Category] B형 간염, [키워드] Liver fibrosis Logistic regression analysis Random Forest algorithm serum ultrasound. [DOI] 10.4103/jcrt.jcrt_1394_22 PMC 바로가기
Clinical utility of circulating calprotectin to assist prediction and monitoring of COVID-19 severity: An Italian studyArticle Published on 2022-12-012022-11-15 Journal: Journal of medical virology [Category] 바이오마커, [키워드] Administered Admission assist Biomarker calprotectin Care chemiluminescent immunoassay circulating Circulating calprotectin clinical Cohort collected Concentration controls correlation COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients disease severity evaluate healthy individual ICU intubation Italian study median Patient positive airway pressure Respiratory Support risk risk assessment. Sample serological serum severity of COVID-19 Severity of disease significantly higher tested utility were used [DOI] 10.1002/jmv.28056 PMC 바로가기
A six-month study of anti-SARS-CoV-2 BNT162b2 mRNA vaccination: A comparative analysis of essential trace elements and anti-RBD IgG sera levelsArticle Published on 2022-12-012022-11-15 Journal: Journal of trace elements in medicine and biology [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] (Post)vaccinal immunity adaptive Analysis analyzed Anti-RBD IgG anti-SARS-CoV-2 anti-SARS-CoV-2 IgG Antibody detection Antibody titers association biochemical BNT162b2 mRNA BNT162b2 mRNA vaccine changes in Concentration Cu Effect elevated Essential Essential trace elements expressed female follow-up period glycoprotein healthy HEK-293 human serum IgG antibody Immunity immunization investigated mRNA vaccine mRNA vaccine. not affected observation period produced producing Protein purified RBD Receptor binding domain remained SARS-CoV-2 sera serum specific IgG antibody spike T cells Total Trace element vaccination Vaccine Volunteer women Zn [DOI] 10.1016/j.jtemb.2022.127079 PMC 바로가기
Immunogenicity and protectivity of intranasally delivered vector-based heterologous prime-boost COVID-19 vaccine Sputnik V in mice and non-human primatesArticle Published on 2022-12-012022-11-15 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] accompanied Blood clinical investigation Coverage COVID-19 COVID-19 pandemic COVID-19 vaccine cytokine release Diseases effective effort elicit Gam-COVID-Vac Health heterologous prime-boost IgA antibody IgG immune response Immunity immunization immunogenic immunogenicity Infection intranasal intranasal vaccine. intranasally K18-hACE2 transgenic mice less lung immunopathology mice mononuclear cell Mortality mucosal nasal mucosa neutralizing antibody non-human primate pandemic Peripheral blood Prevent proliferation protective immunity provided revaccination robust SARS-CoV-2 SARS-COV-2 infection SARSCoV-2 serum Sputnik V systemic and local the vaccine Transmission vaccination Vaccination strategy Vaccine vaccine candidate variants of concern virus virus infection virus spread [DOI] 10.1080/22221751.2022.2119169 PMC 바로가기
Altered kidney function induced by SARS-CoV-2 infection and acute kidney damage markers predict survival outcomes of COVID-19 patients: a prospective pilot studySARS-COV-2 감염 및 급성 신장 손상 마커에 의해 유도 된 변경된 신장 기능 COVID-19 환자의 생존 결과를 예측합니다 : 전향 적 파일럿 연구Article Published on 2022-12-012022-08-31 Journal: Renal failure [Category] COVID19(2023년), SARS, 바이오마커, [키워드] acute kidney Acute kidney injury adjusted Advancing age Altered Analysis association Biomarker chronic Chronic kidney disease collaboration Comorbidities Comorbidity Control coronavirus disease Coronavirus disease 2019 covariate covariates COVID-19 COVID-19 patient COVID-19 patients creatinine Cumulative rates cystatin C death demonstrated elevated examined group groups Hospitalized ICU intensive care intensive care unit investigated Kaplan-Meier method kidney kidney damage Kidney disease Kidney function Kidney function tests Kidney injury literature marker morbidity multivariable Cox regression outcome participant pilot study predict Predictive Predictive value Proteinuria retained risk factor Risk factors SARS-COV-2 infection serum serum creatinine Sex significant difference statistically subject survival survival analysis survival analysis. the Kaplan-Meier method Treatment Urine with COVID-19 [DOI] 10.1080/0886022X.2022.2032743 PMC 바로가기 [Article Type] Article
Association of iron-related biomarkers with severity and mortality in COVID-19 patientsArticle Published on 2022-12-012022-11-15 Journal: Journal of trace elements in medicine and biology [Category] COVID19(2023년), SARS, 바이오마커, 치료기술, [키워드] Activation Analysis analyzed association AUC biological processes Biomarker can be used characterized Combination continuous monitoring contribute Control controls Course COVID COVID 19 COVID-19 COVID-19 patient cutoff point Deceased decrease deficiency demonstrated discharged ferritin healthy individual highest IL-6 immune responses immune system immunomodulatory individual infected with COVID-19 Infection Inflammation iron marker material Mild moderate Mortality multiple regression model outcome oxidative stress parameter patients with COVID-19 receiver operating characteristic recruited regulate required ROC ROC Curve SARS-CoV-2 patients sensitivity serum severe disease severity shown significant difference significantly significantly increased specificity stepwise AIC selection survival susceptibility the cytokine storm the median trace Trace element Trace metals Transferrin Transferrin. variable variety viral infections [DOI] 10.1016/j.jtemb.2022.127075 PMC 바로가기
Neutralizing response elicited by homologous and heterologous prime booster vaccination against ancestral SARS-CoV-2 B.1, P.1, C.37 and B.1.617.2 variantsArticle Published on 2022-11-082022-11-15 Journal: Vaccine [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] analysed B.1 B.1.617.2 BBIBP-CorV booster vaccination ChAdOx1-S Combination country COVID-19 elicited exhibited Gam-COVID-Vac greater Heterologous heterologous vaccination homologous immunized information mRNA-1273 mRNA-1273 vaccines Neutralizing Neutralizing antibodies non-replicative P.1 participant percentage Population protocol protocols provided SARS-CoV-2 second dose serum shortage significantly significantly lower vaccination Vaccination strategies Vaccination strategy Vaccine variant variants of concern. viral vector-based [DOI] 10.1016/j.vaccine.2022.10.021 PMC 바로가기